HGH Fragment 176-191

HGH Fragment 176-191 Basic Information

 

Purity: 98%+

Specification: 2mg/vial

Storage: Closed, below 2 ~ 8 degree preservation

HGH Frag 176-191 is a peptide that has been studied for its potential in enhancing the anticancer efficacy of doxorubicin, a clinical chemotherapeutic drug. In silico analysis suggested that the addition of hGH Frag 176-191 to doxorubicin-loaded Chitosan nanoparticles can enhance doxorubicin binding to multiple breast cancer protein targets . These dual-loaded Chitosan nanoparticles demonstrated greater anti-proliferative activity against a breast cancer cell line (MCF-7) than doxorubicin-loaded Chitosan alone . Additionally, hGH Frag 176-191 has been found to be a peptide that is 10 times more potent than intact hGH in causing glucose intolerance in an animal model. It has been detected in human blood, with higher concentrations observed in pregnant women.

HGH fragment 176-191 is an analog of the growth hormone-releasing factor (GRF) which signals the effects of growth hormone. It is a 15-mer peptide residue of the C-terminus of HGH to which tyrosine is added at the N-terminal end. This synthetically produced hormone is very common to weightlifters and bodybuilders because of a number of physical benefits. Studies claimed that it actually acts on the reduction of excessive adipose tissues such as those in the abdominal area, increase in muscle mass, and enhances the lipid content of the body.

HGH Frag 176-191 is a fragment of the HGH peptide. Scientists found that if they truncated the peptide at the C terminal region they could isolate the fat loss attributes associated with HGH. Taking this fragment from HGH, including the peptide bonds from 176-191, they found they had developed a peptide that regulated fat loss 12.5 times better than regular HGH.

There is no question as to why bodybuilders of the modern era utilize human growth hormone. Its ability to regulate fat loss, pack on size and increase IGF-1 levels is just a few of the many attributes that many seek. HGH Frag 171-191 was developed so that bodybuilders and athletes not looking for the growth properties from HGH could still reap all the results of its amazing fat loss properties.

The (hgH fragment 176-191) exhibits the ability to burn through stubborn adipose tissue, while increasing energy expenditure, muscle mass, and fat oxidation. All studies have pointed to the fact that the fragment is an effective treatment for obesity and fat loss, and much safer than its Human Growth Hormone counterpart.

Growth Hormone peptide fragment 176-191, also known as HGH Frag 176-191, is a modified form of amino acids 176-191 of the GH polypeptide. The fat-reducing effects of GH appear to be controlled by a small region near one end of the Growth Hormone molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears to have no effect on growth or insulin resistance. It works by mimicking the way natural Growth Hormone regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified Growth Hormone. Like Growth Hormone, the hgH fragment 176-191 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in animals and humans.

HGH Frag is like all of the other peptides we have covered and come as a delicate lyophilized powder that should be kept out of the light and in a cool dry place. Reconstitution is done with bacteriostatic water or sodium chloride meant for injection. In order to reap the benefits of HGH Frag, users will need to dose around 500mcgs per day. This can be done by dosing 250mcgs in the morning pre-workout, and 250mcgs before lunch or 250mcgs before bed. Users will also want to take note of the timing of injections and their diet at that time. It is optimal to inject HGH Frag 176-191 on an empty stomach or with just protein in the stomach. Like other peptides, HGH Frag has been noted to not work as effectively in the presence of carbohydrates and sugars.

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